Experience and execution
Jason Fried over at the 37signals blog makes a comment that you've likely heard before, but applies to anyone who is interested in starting a technology business. Pondering whether AOL or Microsoft can compete with YouTube's success in the on-line video market, he states:
"Can AOL and Microsoft beat YouTube down the road? Anything is possible, but they’re making it awful hard on themselves if they think technology is what’s going to win this race. Technology rarely wins the race — experience and execution does. YouTube nailed that. Time will tell if they nailed a few coffins at the same time."
Experience and execution... many would say it's the execution that is a real entrepreneur's calling card. Entrepreneurs do. They "make something happen" as Seth Godin encourages. Even if you don't have the experience, getting out there and starting something will put you in a place where you will learn what you need to know.
"Technology rarely wins the race?" That's another one to remember. As someone who is knee-deep in the creation of software, it's all too easy to get caught up in new technologies for the sake of new technologies. Focusing on the end product and just making something with whatever tools are at hand is likely a better way to get things going.

